Nixxi Health
Nixxi Health

Premature Birth: A Persistent Problem

Preterm birth continues to be a significant public health problem.

The persistently high rates of premature birth are partly due to an inability to identify women at risk for premature delivery from early in pregnancy. Currently, a healthcare provider’s ability to give a patient an assessment of their risk of preterm birth will depend on the gestational age of the pregnancy.

Early in the pregnancy, the standard approach to risk assessment is based on a woman’s history of preterm birth (history-based screening). History-based screening is a simple approach, but it misses 93% of premature births and cannot be used for women in their first pregnancy (first time moms comprise 40% of pregnancies).

As pregnancy progresses, additional tools become available to assess a woman’s risk of preterm birth, but often are not used until the patient already has symptoms of preterm labor.

Nixxi Health
Nixxi Health

Risk Assessment for Premature Birth

Current methods of screening fail to identify 93% of preterm births.

In the United States, nearly 1 in 10 women will deliver prematurely. Rates of preterm birth vary throughout the USA, and are tracked annually by the March of Dimes.

Common risk factors for premature birth include prior preterm birth, pregnancy with twins or other multiples, a short interval between pregnancies, fertility treatments, and problems with the major organs involved in pregnancy. Smoking, drug use, not maintaining a healthy weight, and stress can all contribute to premature birth risk as well. Lifestyle choices and decision-making can play a critical role in eliminating some of these risk factors and give women a better chance of having a healthy pregnancy and baby.

Premature babies often require prolonged hospital stays to overcome acute medical issues and the need to mature in a safe environment. The sequelae of prematurity (bronchopulmonary dysplasia, respiratory distress syndrome, sepsis, intraventricular hemorrhage, necrotizing enterocolitis, retinopathy, among others) may lead to long-term complications requiring medical care beyond the neonatal period.

While the economic impact of premature birth has been estimated to be in excess of $26 billion, the emotional strain on families cannot be adequately quantified. As clinicians, we strive to protect the health and well-being of our pregnant patients and their children.

Nixxi Health
Nixxi Health

Nixxi’s Platform Fills the Gap in Care

Nixxi Health

The first digital health screening tool to risk-stratify pregnancies for preterm birth outcomes

Available Now
Nixxi Health

Personalized, expert guidance to simplify and optimize pregnancy management

Trial Phase
Nixxi Health

Accurately identify pregnancies at the highest risk for very preterm birth and neonatal morbidity

Coming Soon
Nixxi Health

The first digital health screening tool to risk-stratify pregnancies for preterm birth outcomes

Available Now
Nixxi Health

Personalized, expert guidance to simplify and optimize pregnancy management

Trial Phase
Nixxi Health

Accurately identify pregnancies at the highest risk for very preterm birth and neonatal morbidity

Coming Soon
Nixxi Health

The PopNatal Difference

PopNatal is a clinical decision support tool intended to inform health care provider management of pregnant women.

Using a proprietary algorithm to analyze hundreds of different demographic, medical, and behavioral factors, PopNatal is able to identify women with an elevated risk of premature delivery before 37 weeks’ gestation.

As a digital health tool, PopNatal is convenient for your patients to complete and can be administered from the very beginning of the pregnancy.

Compared to history-based screening at the beginning of pregnancy (7% sensitivity), PopNatal demonstrates a 10-fold increase in sensitivity (75% sensitivity) –this means that more women who will go on to deliver preterm are identified early.

Risk stratification of your patients from early in pregnancy is important. Published studies have demonstrated that treatment of women at high risk for preterm delivery with a bundle of clinical interventions can be an effective approach.

The care bundle utilized in these studies included cervical length screening, pharmacologic treatments with vaginal progesterone or 17P as indicated, screening and treatment of vaginitis, and treatment of medical comorbidities. The utilization of these approaches in women at high risk for preterm delivery resulted in up to a 30% reduction in early preterm births.

PopNatal makes it feasible to screen your patients and identify those with elevated risk that may benefit from enhanced care.

Interested in Offering PopNatal to Your Patients?