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The first digital health screening, prenatal care tool to risk-stratify pregnancies for preterm birth outcomes


Curated evidence-based guidelines to optimize pregnancy management

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Accurately identify pregnancies at the highest risk for very preterm birth

Simple.  Accurate.  Actionable.

Prenatal Care Solutions

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PopNatal uses a proprietary algorithm to analyze hundreds of different demographic, medical, and behavioral factors. 

The result is an ability to identify women with a high risk of preterm delivery (<37 weeks’ gestation) from pre-conception or the beginning of pregnancy, without needing a blood draw, and from the convenience and comfort of a woman’s own home, offering the ultimate in prenatal care.

Convenient interface encourages patient engagement
Available pre-conception or at onset of pregnancy

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Simplified, convenient prenatal care reporting

Results That Matter

Early identification of pregnancies at risk for preterm birth gives prenatal care providers more time to create personalized care plans and improve outcomes.

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10-fold increased sensitivity to predict preterm birth compared to history-based screening in early pregnancy

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High-Risk Result

4-fold increased risk of preterm birth before 37 weeks (p<0.0001)

Low-Risk Result

96% chance of delivering full term

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Gain Insight Pre-conception

Provides prenatal care intelligence at the very beginning of pregnancy or pre-conception to optimize the chances of reaching full-term

PopNatal Allows Women to Take Charge of Their Pregnancy

How it Works

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PopNatal Insights provides expert-level guidance for prenatal care tailored to your health profile. This customized report gives your healthcare provider a roadmap based on the latest evidence-based guidelines.


  • Counseling pearls – Perinatology-level notes to guide the discussion between patient and healthcare provider
  • Recommended actions – Evidence-based guidelines to optimize prenatal care
  • References – Transparency regarding peer-reviewed literature sources
  • Timeliness – Patient-specific guidance at your health care provider’s fingertips from the beginning of pregnancy
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Currently under final development, DocNatal is poised to pinpoint the highest risk pregnancies – those likely to result in delivery at or under 32 weeks’ gestation. This category, frequently called Very Preterm Birth, represents the most serious pregnancy cases which are closely linked to increased neonatal complications and lengthy NICU stays. Nixxi expects that pregnant women can take DocNatal in the late first trimester. The early identification of these situations will allow women and clinicians to have an opportunity to put together very thoughtful and comprehensive pregnancy care plans.

Click here to read Nixxi’s press release concerning this important research and click here to read the peer-reviewed paper detailing the science itself.

The maternal/fetal HPA axis is known to influence the timing of delivery.

Nixxi capitalizes on a novel discovery that advances prior literature.

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